Steroids and derivatives
Medchemexpress LLC 17β-Estradiol sulfate-d4 sodium | 352431-50-6 | 99.57% | C18H19D4NaO5S | 1 MG
17β-Estradiol sulfate-d4 sodium is the deuterium labeled form of 17β-Estradiol sulfate. This compound, also known as β-Estradiol 3-sulfate sodium salt, functions as a neuroactive steroid, making it relevant for research in neuroscience and steroid biology.
- Deuterium labeled compound for specialized research
- Functions as a neuroactive steroid
- Also known as β-Estradiol 3-sulfate sodium salt
Medchemexpress LLC β-Estradiol 17-hemisuccinate | 7698-93-3 | 98.8% | 372.45 | 25 MG
β-Estradiol 17-hemisuccinate is a synthetic derivative of estradiol. It is designed for research use and is stored at 4°C under nitrogen. When in solvent, it is recommended to store it at -80°C for up to 6 months or -20°C for up to 1 month, also under nitrogen.
- Synthetic derivative of estradiol
- Stored at 4°C under nitrogen
- In solvent, stable for 6 months at -80°C
- In solvent, stable for 1 month at -20°C
Santa Cruz Biotechnology β-Estradiol 3-sulfate sodium salt, 25 mg | CAS# 4999-79-5
β-Estradiol 3-sulfate sodium salt functions as a steroid hormone and exhibits estrogenic activity. It acts by binding to estrogen receptors, estrogen receptor alpha and beta, within the cell nucleus. This binding initiates a cascade of molecular events, leading to the regulation of gene expression and the modulation of various cellular processes. β-Estradiol 3-sulfate sodium salt′s mechanism of action involves influencing the transcription of target genes, thereby impacting the physiological responses of the cells. By interacting with estrogen receptors, β-Estradiol 3-sulfate sodium salt plays a role in the regulation of cell proliferation, differentiation, and apoptosis. Its activity at the molecular level contributes to the modulation of various signaling pathways and cellular functions, making it a relevant component in studies exploring hormone signaling and related biological processes.
Medchemexpress LLC Estradiol 3-methyl ether | 1035-77-4 | 99.9% | 286.41 | 50 MG
Estradiol 3-methyl ether is a synthetic estrogen. It can disrupt microtubule networks in V79 cells with an EC50 of 9 μM, and it also inhibits cell proliferation. Additionally, Estradiol 3-methyl ether has been shown to decrease serum cholesterol levels and increase body weight loss, indicating feminizing activity in an HFD murine model.
- Synthetic estrogen
- Disrupts microtubule networks in V79 cells with an EC50 of 9 μM
- Inhibits cell proliferation
- Decreases serum cholesterol levels in HFD murine model
- Increases body weight loss in HFD murine model
- Indicates feminizing activity in HFD murine model
Medchemexpress LLC Estradiol enanthate (E2EN) | 4956-37-0 | 98.1% | 100 MG
Estradiol enanthate (E2EN) is a shorter-acting estrogen. It is an injectable contraceptive when combined with Dihydroxyprogesterone acetophenide. Estradiol enanthate facilitates withdrawal bleeding, mimicking a menstruation-like pattern.
- Shorter-acting estrogen.
- Functions as an injectable contraceptive in combination with Dihydroxyprogesterone acetophenide.
- Promotes withdrawal bleeding, in a pattern similar to menstruation.
- Changes the corporal characteristics of male rats to resemble female rats.
- In a study, it increased plasma urea and creatinine concentration compared to the control group.
Cayman Chemical 17-EstradIol-d3 25mg
An internal standard for the quantification of 17β-estradiol by GC- or LC-MS
Apexbio Technology LLC Estradiol 50-28-2 10mM (in 1mL DMSO)
Estradiol is an endogenous steroid hormone involved in the regulation of reproductive biology and cellular physiology through interaction with estrogen receptor (ER) subtypes and Estradiol binding to ER initiates genomic and non-genomic signaling pathways influencing transcription of diverse target genes related to proliferation differentiation and metabolism Estradiol-mediated ER signaling modulates cellular processes including epithelial-mesenchymal transition endothelial function oxidative stress responses and gene expression profiles in various cell lines such as HEK293 and U2OS Additionally estradiol treatment regulates cardiovascular function by inducing mitochondrial superoxide dismutase (SOD2) implicating protective effects in vascular conditions Estradiol exhibits ER subtype selectivity with reported ER and ER binding affinities (IC50) around 0 2-0 5 nM utilized broadly in estrogen signaling research and cardiovascular disease modelling
Sigma Aldrich Fine Chemicals Biosciences 17alpha-Ethynylestradiol >=98% | 57-63-6 | MFCD00003690 | 10G
17alpha-Ethynylestradiol >=98% | Purity: >=98% | Mol Wt: 296.4 | 57-63-6 | MFCD00003690 | 10G
Medchemexpress LLC β-estradiol-6-one 6-(O-carboxymethyloxime) | 35048-47-6 | MFCD00056459 | 99.7% | 359.42 g/mol | C20H25NO5 | 5 MG
β-Estradiol-6-one 6-(O-carboxymethyloxime) is an estradiol-derived small molecule functionalized at the 6-position with an O-carboxymethyloxime moiety. It is used as an alkyl chain-based PROTAC linker and building block for synthesizing targeted protein degradation constructs. Provided for research use only.
- Designed as an alkyl chain-based PROTAC linker for conjugation chemistry.
- High purity suitable for analytical and synthetic applications.
- Solid form, easy to handle and store.
- Molecular formula C20H25NO5 and molecular weight 359.42 g/mol.
- Available in small pack sizes for research and method development.
Cayman Chemical Ethynyl Estradiol
An estrogen receptor agonist (EC50 = 8.5 pM in a reporter assay using T47D cells); reduces serum cholesterol levels and femur bone mass and increases uterine mass in an OVX rat model of postmenopause at 0.1 mg/kg per day; has been found in wastewater effluent; prevents secondary sexual development in male fathead minnows and increases the numbers of intersex fish at 4 ng/l
Selleck Chemical LLC Estradiol Cypionate S4046-50mg
Estradiol cypionate is the 17 -cyclopentylpropinate ester of estradiol which inhibits ET-1 synthesis via estrogen receptor
Apexbio Technology LLC Mifepristone, 100mg. Cas: 84371-65-3 MFCD: MFCD00867226. Progesterone receptor antagonist
Mifepristone (RU486) is a potent antagonist of progesterone receptor, used as a contraceptive agent. 84371-65-3. MFCD00867226
Apexbio Technology LLC Cyproterone Acetate 427-51-0 250mg
Cyproterone Acetate (CAS 427-51-0) is a small-molecule antagonist targeting the androgen receptor (AR) It is designed to inhibit AR activation thereby suppressing androgen-mediated cellular signaling Cyproterone Acetate exerts its biological activity primarily through competitive binding to AR displacing endogenous androgen ligands and blocking receptor activation and downstream signaling In experimental assays Cyproterone Acetate demonstrates AR inhibition with an IC50 value of approximately 7 1 nM At higher concentrations (EC50 around 4 0 M) it may also exhibit partial agonist activity on the AR pathway Based on these pharmacological properties Cyproterone Acetate holds research potential in studies of androgen-dependent biological processes AR signaling mechanisms and hormone-sensitive pathologies such as prostate cancer or androgen-related metabolic conditions
Apexbio Technology LLC Ouabain,50mg CAS# 630-60-4
Ouabain is a selective Na+/K+, -ATPase inhibitor, binds to α2 /α3 subunit with Ki of 41 nM/15 nM. Other sizes are also available. Please inqury us for quote.